In vivo immunofluorescence to diagnose herpes simplex virus keratitis in mice
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چکیده
منابع مشابه
In vivo immunofluorescence to diagnose herpes simplex virus keratitis in mice.
BACKGROUND/AIMS Herpes simplex virus keratitis (HSK) is the most common cause of corneal blindness in the Western world. Delay in the treatment of HSK can lead to a more significant corneal scar and topical steroid treatment in unsuspected active HSK can lead to corneal melting. Current culture techniques for herpes simplex virus (HSV) take several days and commercially available HSV laboratory...
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The authors have investigated the course of herpes simplex type 1 (HSV) keratitis in three different inbred strains of mice infected with four different HSV isolates. Severity of ocular disease and mortality is dependent upon both the virus isolate and the host strain. In particular, the likelihood of progression from self-limited dendritic keratitis to severe necrotizing stromal keratitis vari...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1997
ISSN: 0007-1161
DOI: 10.1136/bjo.81.9.785